For couples struggling to have a child, IVF is undeniably one of the most popular solutions available. It doesn’t always guarantee success, but most couples normally conceive within three cycles of IVF. However, sometimes, even three IVF cycles can fail. In most cases, this inability to conceive may be linked to endometrial receptivity, in which case the embryo misses the window of implantation and the embryo is unable to implant.
It is very important for the timing of embryo transfer to correspond with the woman’s window of implantation. It mustn’t be too late or too late, but just right on time. This timing may be different for some people.
An Endometrial Receptivity Analysis (ERA) test is used to both evaluate endometrial receptivity as well as predict the exact time an embryo transfer will produce the best chance of a successful implantation and pregnancy.
By endometrial receptivity, we mean the extent of receptivity of the endometrial lining in the uterus. ERA checks whether the lining is receptive enough to accept the embryo. This is usually done by analyzing the expression of 238 genes that are connected with endometrial receptivity at molecular level.
Through the test, our doctors can determine the personalized window of the woman and know when to transfer an embryo to the uterus so that it sticks and grows.
In other words, ERA is done to ensure a successful implantation and minimize the chances of a failed pregnancy.
We can check for the receptivity of the endometrium before starting an IVF procedure and mimic the same during the embryo transfer.
ERA testing can be beneficial for patients who have had three or more IVF cycles without success. It is assumed that fertilization was successful and healthy embryos were transferred. But still the woman experienced repeated implantation failure.
Patients also undergoing IVF or other ART treatments for the first time can also undergo an ERA test to maximize their chances of pregnancy.
With all the benefits of ERA testing, it is also worth noting that the procedure can cause slight discomfort although no medical side effects are expected. The pain is usually as a result of the uterine biopsy carried out to collect the endometrial tissue from the uterus.
It has been suggested that three out of every ten women have a displaced implantation window. By opting for an ERA test, you can avoid implantation failure.
At Archish IVF, we help establish the best day for your embryo transfer so that successful implantation can occur. You can book an appointment today and speak to one of our doctors for more information.